San Francisco 49ers vs Atlanta Falcons Predictions, Picks, Odds, and Betting Preview | NFL Week 6 – October 16, 2022

The San Francisco 49ers failed to extend their win streak to three games after losing to the Baltimore Ravens on the road last Sunday, 19-17. They will look to get back to their winning ways when they square off with the Atlanta Falcons, who just snapped a three-game losing skid by beating the Seattle Seahawks at home in Week 6, 39-32. Check out our preview of this 49ers vs Falcons game in Week 6 of the 2022 NFL regular season.

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Betting Preview for the San Francisco 49ers vs Atlanta Falcons Week 6 Game on October 16, 2022

Where: Mercedes-Benz Stadium, Atlanta, Georgia

When: Sunday, October 16, 2022, 1:00 PM ET

Line: San Francisco 49ers (-6.0) vs Atlanta Falcons (+6.0) – view all 2022 NFL lines

TV Broadcast: FOX

Betting on the San Francisco 49ers (-6.0)

Regular Season Record: 3-2

Jimmy Garoppolo passed for 253 yards and two touchdowns with zero interceptions on 18/30 completions against Carolina. That’s an encouraging sight for the 49ers going into Week 6. Another standout player for the team in that game was running back Jeff Wilson Jr., who rushed for 120 yards and a touchdown on 17 carries. That means he averaged 7.1 yards per carry. But it’s San Francisco’s defense that could be more terrifying to the Falcons. The Niners sacked Carolina quarterbacks for a total of six times and held the Panthers to just 3/15 on third downs.

The 49ers are 3-1 against the spread in their last four games overall.

Betting on the Atlanta Falcons (+6.0)

Regular Season Record: 2-3

The Falcons picked up another loss this season in the Tampa Bay game, but they were competitive in that contest. They made it interesting in the fourth quarter where they put up 15 unanswered points. Atlanta has three losses this season, but they have yet to be blown out, which says a lot about why this is a team that is always a landmine waiting to get stepped on by opponents who are favored to win. In fact, the Falcons have covered the spread in all of their five games to date this season.

The Over is also 4-2 in the Falcons’ last six games overall, dating back to 2021.

Writer’s Prediction

The 49ers win, 23-17.

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