San Francisco 49ers vs Minnesota Vikings Predictions, Picks, Odds, and Betting Preview | NFL Preseason Week 2 – August 20, 2022

Week 2 of the 2022 NFL preseason also features a showdown between the San Francisco 49ers and the Minnesota Vikings. Check out our preview below of this 49ers vs. Vikings 2022 preseason game.

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Betting Preview for the San Francisco 49ers vs Minnesota Vikings Preseason Week 2 Game on August 20, 2022

Where: U.S. Bank Stadium, Minneapolis, Minnesota

When: Saturday, August 20, 2022, 7:00 PM ET

Line: San Francisco 49ers (-7) vs Minnesota Vikings (+7) – view all 2022 NFL lines

TV Broadcast: NFL Network

Betting on the San Francisco 49ers (-7)

Regular Season Record: 1-0

The 49ers won their last game, 28-21, against the Green Bay Packers at home in Week 1 of the preseason. The Niners collected 328 total yards and gave up a total of 437 to the Packers. They also forced three turnovers and went 7/14 on third downs.

The 49ers are 5-0 against the spread in their last five games overall.

Betting on the Minnesota Vikings (+7)

Regular Season Record: 0-1

The Vikings lost to the Las Vegas Raiders on the road in Week 1 of the preseason. They were outgained by Las Vegas but only 300-298. Kellen Mond went 9/14 for 119 passing yards and two touchdowns for the Vikings, who struggled on third downs, converting just 1 of 7 attempts in those scenarios. But were able to average more yards per pass than the Raiders (6.5 to 5.2).

The Over is 4-0 in Minnesota’s last four games at home.

Writer’s Prediction

The 49ers win, 20-17.

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