Buffalo Bills vs Detroit Lions Predictions, Picks, Odds, and Betting Preview | Week 12 – November 24, 2022

The Buffalo Bills are coming to Detroit for Thanksgiving for a showdown with the suddenly resurgent Detroit Lions. Will the Bills humble Detroit? Or will the Lions continue their hot streak? Check out our preview of this Bills vs Dolphins game in Week 12 of the 2022 NFL regular season.

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Betting Preview for the Buffalo Bills vs Detroit Lions Week 12 Game on November 24, 2022

Where: Ford Field, Detroit, MI

When: Thursday, November 24, 2022, 12:30 PM ET

Line: Buffalo Bills (-9.0) vs Detroit Lions (+9.0) – view all 2022 NFL lines

TV Broadcast: CBS

Betting on the Buffalo Bills (-9.0)

Regular Season Record: 7-3

After losing two in a row, the Bills are back to their winning ways, as they defeated the Cleveland Browns in Detroit in Week 11, 31-23. With that game being relocated to Motor City due to snow in the Buffalo area, the Bills had sort of a free warmup in Detroit before facing the home team this coming Thursday. The tandem of Devin Singletary and James Cook did most of the work on offense in that game, combining for 174 rushing yards and a touchdown on 29 carries. But the Bills can find offense from basically anyone from the team, especially against lousy offenses. Detroit, meanwhile, happens to have one of the worst defenses in the NFL.

The Under is 5-0 in the Bills’ last five road games.

Betting on the Detroit Lions (+9.0)

Regular Season Record: 4-6

The Lions are winning. Suddenly, they have four wins, three of which came in their last three games. Their latest victims were the New York Giants on the road in Week 11, 31-18. Detroit’s last two wins also were on the road, so the Lions must be feeling good as they fly back home for Thanksgiving with that kind of momentum. The Lions’ success is being driven by their productive offense and a defense that is starting to show some signs of life. Over their last three games, the Lions have averaged 25.66 points while allowing just 19 points. Against the Giants, the Lions forced three New York turnovers.

The Lions are 7-3 against the spread in their last 10 home games.

Writer’s Prediction

The Bills win, 30-20.

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