Buffalo Bills vs Kansas City Chiefs Predictions, Picks, Odds, and Betting Preview | NFL Week 5 – October 10, 2021

The Kansas City Chiefs will look to go over .500 when they face the streaking Buffalo Bills in Week 5 at Arrowhead Stadium. This matchup has the potential to be a preview of the AFC Championship Game, so make sure not to miss this contest. Check out our preview of this contest below.

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Betting Preview for the Buffalo Bills vs Kansas City Chiefs Regular Season Week 5 Game on October 10, 2021

Where: GEHA Field at Arrowhead Stadium, Kansas City

When: Sunday, October 10, 2021, 8:20 PM ET

Line: Buffalo Bills (+2.5) vs Kansas City Chiefs (-2.5) – view all 2021 NFL lines

TV Broadcast: NBC

Betting on the Buffalo Bills (+2.5)

Regular Season Record: 3-1

The Bills showed no mercy for the Houston Texans in Week 4. Behind a relentless offense and an unforgiving defense, Buffalo scored a 40-0 victory over the Texans last Sunday for the Bills’ third win in a row. Dawson Knox had a field day in the end zone as he caught two touchdowns on five catches and eight targets from Josh Allen, who went 20/29 for 248 yards with an interception. Although Buffalo will be facing a much tougher offense in Week 5 in the form of the Chiefs, the Bills can still limit Kansas City’s time of possession by extending plays against their opponent that’s second-worst in the league in scoring defense. The Chiefs are allowing 31.2 points per game and nearly 440 total yards per contest. Kansas City’s defense is looking very tasty for Allen and the rest of the Bills’ attack that features so many weapons downfield, including Knox, Emmanuel Sanders, and of course, Stefon Diggs.

The Bills are 5-1 against the spread in their last six road games.

Betting on the Kansas City Chiefs (-2.5)

Regular Season Record: 2-2

The Chiefs prevented what would have been a devastating three-game losing streak, as they scored a huge 42-30 road win over the Philadelphia Eagles in Week 4. That came after the Chiefs suffered back-to-back losses to the Baltimore Ravens and the Los Angeles Chargers. Tyreek Hill embarrassed Philly’s defense as he finished with 186 receiving yards and three touchdowns on 11 receptions and 12 targets. The Bills are allowing just 11.0 points per game and 148.8 passing yards per contest, but they haven’t really been tested defensively out of their Week 1 upset loss to the Pittsburgh Steelers. Since then, the Bills have only beaten the Miami Dolphins, Washington Football Team, and the Texans. Washington is 19th in the league in passing yards per game, Miami is 30th, while Houston is 29th. As for the Chiefs, they are fifth with 297.2 passing yards per game.

The over is 2-1 in the Chiefs’ last three home games.

Writer’s Prediction

The Chiefs win, 33-30.

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