Denver Broncos vs Buffalo Bills Predictions, Picks, Odds, and Betting Preview | NFL Preseason Week 2 – August 20, 2022

The Denver Broncos and the Buffalo Bills are still hunting for win no. 1 in the 2022 NFL preseason. Which team will get that this Friday? Check out our preview below of this Broncos vs. Bills 2022 preseason game.

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Betting Preview for the Denver Broncos vs Buffalo Bills Preseason Week 2 Game on August 20, 2022

Where: Highmark Stadium, Orchard Park, New York

When: Saturday, August 20, 2022, 1:00 PM ET

Line: Denver Broncos (odds) vs Buffalo Bills (odds) – view all 2022 NFL lines

TV Broadcast: NFL Network

Betting on the Denver Broncos (odds)

Regular Season Record: 1-0

The Broncos whipped the Dallas Cowboys last Saturday in a 17-7 victory to win their first preseason outing this year. Denver has now gone undefeated in all of its last five preseason games, dating back to 2021. With Russell Wilson still to make his preseason debut for the Broncos, journeyman quarterback Josh Johnson took advantage of the opportunity and passed for 172 yards and two touchdowns on 16/23 completions against the Cowboys. The Broncos, however, would love to see more from their ground attack that put up just 39 rushing yards on 22 carries against Dallas. Javonte Williams and Melvin Gordon both did not play, but even then, not averaging at least two yards per carry is unacceptable for Denver. In any case, the Broncos have to like what they did defensively versus the Cowboys, and they will look to sustain that heading to Week 2.

The Broncos are 4-1 against the spread in their last five preseason games. The Under is also 9-1 in Denver’s last 10 games in the preseason.

Betting on the Buffalo Bills (odds)

Regular Season Record: 1-0

Buffalo scored win no. 1 in the 2022 NFL preseason by handing the Indianapolis Colts a 27-24 defeat last Saturday at home. The Bills have won all of their last nine preseason games, a streak that started way back in 2018. Josh Allen did not play in that game, while Matt Barkley and Case Keenum split the quarterbacking duties. Barkley went 18/24 for 224 yards and zero touchdowns with an interception. Keenum was 11/18 for 86 passing yards, zero touchdowns, and two interceptions. That was not ideal for Buffalo, who got away with a win mainly because running back Raheem Blackshear was able to score two rushing touchdowns. Safety Jaquan Johnson also had an interception. Even though their quarterbacks were shaky in Week 1 of the preseason, the Bills will always be a threat to opposing second and third-stringer defensive players because Barkley and Keenum are two highly experienced QBs.

The Bills are 9-0 against the spread in their last nine games in the preseason, with the Over hitting seven times over that same stretch.

Writer’s Prediction

The Bills win, 23-20.

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