Cleveland Guardians vs Chicago White Sox Predictions, Picks, Odds, and Baseball Betting Preview | July 22 2022

The Cleveland Guardians and the Chicago White Sox square off against each other to open the second half of the 2022 MLB regular season. Who kicks off the final half of the campaign with a victory? Check out our preview below of this Guardians vs. White Sox 2022 MLB regular season game.

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Betting Preview for the Cleveland Guardians vs Chicago White Sox MLB Regular Season Game on July 22, 2022

Where: Guaranteed Rate Field, Chicago, Illinois

When: Friday, July 22, 2022, 8:10 PM ET

Line: Cleveland Guardians (odds) vs. Chicago White Sox (-1.5) – view all 2022 MLB lines

TV Broadcast: MLBN/ESPN

Betting on the Cleveland Guardians (odds)

Regular Season Record: 46-44

The Guardians are eyeing to continue their win streak after closing out the first half of the regular season with three wins in a row during a sweep of the Detroit Tigers at home. On the mound for Cleveland this Friday is Cal Quantrill, who owns a 6-5 record with a 3.75 ERA and 1.29 WHIP. The Guardians are actually 2-0 in his last two starts, and that includes their 8-4 victory over the White Sox back on July 11 at home when Quantrill went six innings long and gave up 4 earned runs on 8 hots with 3 strikeouts. Quantrill steps on the hill for this game with the hope that Cleveland’s offense comes through again. Jose Ramirez and Andres Gimenez are expected to step up anew for Cleveland’s offese, as they are hitting .288 and .296 this season, respectively, while combining for 29 home runs and 118 RBIs.

Betting on the Chicago White Sox (odds)

Regular Season Record: 46-46

The White Sox are just three games behind in the American League Central division, so they are still very hopeful they could catch the Minnesota Twins and surpass the Guardians in the group. Their offense has been sort of up and down this season, but they arrived at the 2022 MLB All-Star break ranked third in batting average (.257) and 15th in runs per game (4.41 ). While it’s currently unknown who the White Sox’s starter for this game will be, Chicago is 18th in the majors with a starters’ ERA of 4.07 and also owns a .297BABIP. Jose Abreu and Andrew Vaughnheadline the run support system of the White Sox after hitting .304 and .301 in the first half, respectively, while combining for 21 home runs and 100 RBIs.

Writer’s Prediction

The White Sox win, 6-4.

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