Houston Texans vs Buffalo Bills Predictions, Picks, Odds, and Betting Preview | NFL Week 4 – October 3, 2021

The Buffalo Bills are like a freight train right now following two wins in a row. They will look to win their third straight this weekend against the visiting Houston Texans, who are seeking an upset victory to get them back to .500. Check out our preview of this game below.

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Betting Preview for the Houston Texans vs Buffalo Bills Regular Season Week 4 Game on October 3, 2021

Where: Highmark Stadium, Orchard Park

When: Sunday, October 3, 2021, 1:00 PM ET

Line: Houston Texans (+17) vs Buffalo Bills (-17) – view all 2021 NFL lines

TV Broadcast: CBS

Betting on the Houston Texans (+17)

Regular Season Record: 1-2

Davis Mills was not great but he wasn’t bad either in his first career start in the NFL. Starting in lieu of the injured Tyrod Taylor, Mills went 19/28 for 168 passing yards and a touchdown in Houston’s 24-9 home loss to the Carolina Panthers in Week 3. With Taylor on the injured reserve and Deshaun Watson’s status high up in the air, Mills can look forward to making another start when they take on the Bills on the road. With a start under his belt, perhaps Mills can be more steady with the football this time around. But Houston might also go back to its run-heavy ways just like what they did in Week 1’s win over the Jacksonville Jaguars. Say what you want to say about the Texans’ backfield, but the trio of Mark Ingram, David Johnson, and Phillip Lindsay are capable of putting together a terrific performance. Establishing the run early and putting pressure on Buffalo’s defense against the run early could be the key to an upset for Houston.

The Texans are 4-1 against the spread in their last five games as the underdog.

Betting on the Buffalo Bills (-17)

Regular Season Record: 2-1

The Bills seem to have gotten it together after a Week 1 stumble in a 23-16 home loss to the Pittsburgh Steelers. Since then, Buffalo demolished the Miami Dolphins on the road (35-0) then defeated the Washington Football Team at home (43-21). Allen absolutely balled out against Washington, tossing four touchdowns and zero interceptions to go with 358 passing yards on 32/43 completions. On top of that, he also rushed for a touchdown. Can he duplicate that against Houston’s defense? With an assortment of weapons downfield plus Allen’s mobility, it’s not hard to imagine him putting on another show this coming weekend. Buffalo can have control of the ball a lot more than usual against Houston because the Bills have what it takes to make plenty of stops. For one, Mills is looking like a sitting duck for Buffalo’s pass rush. Mills got sacked four times by Carolina while being protected by the Texans’ offensive line that has allowed a sack 6.25 percent of the time.

The Bills are 4-0 against the spread in their last four games against sub-.500 teams.

Writer’s Prediction

The Bills win, 26-10.

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