Indianapolis Colts vs Tennessee Titans Predictions, Picks, Odds, and Betting Preview | NFL Week 7 – October 23, 2022

The Indianapolis Colts and the Tennessee Titans will be meeting for the second time this season. The Titans won the first matchup between these AFC South division rivals in Week 4 in Indianapolis, 24-17. The Colts have gone 2-0 since, including their 34-27 home win over the Jacksonville Jaguars in Week 6. The Titans, on the other hand, stretched their win streak to three games after beating the Washington Commanders in Week 5 (just before a Week 6 bye) on the road, 21-17. Check out our preview of this Colts vs Titans game in Week 7 of the 2022 NFL regular season.

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Betting Preview for the Indianapolis Colts vs Tennessee Titans Week 7 Game on October 23, 2022

Where: Nissan Stadium – Nashville – Formerly LP Field, Nashville, Tennessee

When: Sunday, October 23, 2022, 1:00 PM ET

Line: Indianapolis Colts (+2.0) vs Tennessee Titans (-2.0) – view all 2022 NFL lines

TV Broadcast: CBS

Betting on the Indianapolis Colts (+2.0)

Regular Season Record: 3-3

Even without running back Jonathan Taylor, the Colts managed to overpower the Jaguars in Week 6. Quarterback Matt Ryan was in his vintage form in that game, passing for 389 yards and three touchdowns with zero interceptions on 42/58 completions. Michael Pittman Jr. was fantastic with 134 receiving yards on 13 catches, while Deon Jackson rushed for 42 yards and a touchdown on 12 carries. Taylor could be back in Week 7, so that’s one thing to monitor over on the side of Indianapolis, which outgained Tennessee in the first meeting, 365-243.

The Colts are 3-1 against the spread in their last four games overall.

Betting on the Tennessee Titans (-2.0)

Regular Season Record: 3-2

Derrick Henry rushed for 102 yards and two touchdowns in the Titans’ win over the Commanders in Week 6. Henry is a terrifying running back to deal with for opposing defenses and the Colts know all about that. After all, Henry went off for 114 rushing yards and a touchdown on 22 carries in Week 4’s victory against Indianapolis. Apart from Henry, Tennessee’s defense is also on a groove, as the Titans have not allowed more than 17 points in each of their last two games.

The Titans are 3-0 against the spread in their last three games overall.

Writer’s Prediction

The Colts win, 24-22.

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