Detroit Lions vs Arizona Cardinals Predictions, Picks, Odds, and Betting Preview | NFL Week 3 – September 27, 2020

It wasn’t that long ago when the Detroit Lions baptized Kyler Murray in the NFL last year in a game that ended in a draw. Better, stronger, faster, and surrounded with improved talent, Murray will look to reintroduce himself to the Lions this week, as they host the winless Lions. Will the Cardinals keep their win streak alive? Or will the Lions get their first win of the season?

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Betting Preview for the Detroit Lions vs Arizona Cardinals Regular Season Week 3 Game on September 27, 2020

Where: State Farm Stadium, Glendale

When: Sunday, September 27, 2020, 4:25 PM ET

Line: Detroit Lions (+6) vs Arizona Cardinals (-6) – view all 2020 NFL lines

TV Broadcast: FOX

Betting on the Detroit Lions (+6)

Regular Season Record: 0-2

Lions fans must be so pissed with their team right now, especially with the manner with which Detroit has been losing over its last few games. The Lions lost to the Green Bay Packers at Lambeau Field in Week 2, 42-21, which was the fourth time in a row in which Detroit lost despite holding a double-digit lead, dating back to last season. Matthew Stafford completed 20 of 33 passes for 244 passing yards and two touchdowns with an interception against the Packers, while the ground attack produced just 89 rushing yards on 21 carries, but came away with a touchdown. The Lions’ offense should get a huge boost this week with No. 1 wide receiver Kenny Golladay expected to finally make his season debut after mising the first two games with a hamstring issue. Nothing is set in stone yet with regards to Golladay’s status, but it does appear that he’s good to go against the Cardinals, who just got burned by Washington Football Team’s Terry McLaurin for 125 receiving yards and a TD on seven catches last week.

The over is 2-0 in the Lions’ last two games.

Betting on the Arizona Cardinals (-6)

Regular Season Record: 2-0

The Cardinals continue to surge after taking down Washington in Week 2, 30-15. Kyler Murray is starting to look like a future league MVP, as he’s now among the league leaders in rushing touchdowns while directing Arizona’s offense that’s putting up 27.0 points per game — good for 12th overall in the NFL. Apart from passing for 286 yards (26/38) and a touchdown with an interception in the Washington game, Murray rushed for 67 yards and two touchdowns on eight carries. He now has three rushing touchdowns on the season and his success on the ground could continue against the toothless Lions’ defense. Detroit surrendered 488 total yards to Green Bay last week, including 259 rushing. The Lions are dealing with plenty of injuries on the defensive front, particularly on their secondary, which should be lighting the eyes of DeAndre Hopkins. The wideout has 219 receiving yards and a touchdown on 22 receptions over his first two games in a Cardinals uniform.

The Cardinals are 4-2 against the spread in their last four games overall.

Writer’s Prediction

The Cardinals win, 33-23.

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