Detroit Lions vs Indianapolis Colts Predictions, Picks, Odds, and Betting Preview | NFL Preseason Week 2 – August 20, 2022

The Detroit Lions and the Indianapolis Colts both go for win no. 1 in the 2022 NFL preseason when they face each other this Friday at Lucas Oil Stadium down in Indianapolis, Indiana. Check out our preview below of this Lions vs. Colts 2022 preseason game.

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Betting Preview for the Detroit Lions vs Indianapolis Colts Preseason Week 2 Game on August 20, 2022

Where: Lucas Oil Stadium, Indianapolis, Indiana

When: Saturday, August 20, 2022, 1:00 PM ET

Line: Detroit Lions (odds) vs Indianapolis Colts (odds) – view all 2022 NFL lines

TV Broadcast: NFL Network

Betting on the Detroit Lions (odds)

Regular Season Record: 0-1

Although they lost to the Atlanta Falcons in Week 1 at home, 27-23, the Lions were able to offer a glimpse of what their offense could do when their starters play. Detroit was able to score on its opening drive on a rushing score by running back D’Andre Swift. The Lions have not won a preseason game, though, since 2018 and will look to try again in Week 2 against a Colts team that also struggled last week. There is certainly life in the Lions’ offense that could take advantage of Indianapolis’ stop unit that had just allowed 369 total yards to the Buffalo Bills last Saturday.

The Lions have covered the spread in three of their last four road games in the preseason. The Over is 4-0 in their last four preseason games away from home.

Betting on the Indianapolis Colts (odds)

Regular Season Record: 0-1

The Colts came out on the wrong end of a rather high-scoring showdown with the Buffalo Bills last Saturday, as Indianapolis lost in that game on the road, 27-24. Matt Ryan debuted in Colts uniform and played for some snaps, going 6/10 for 58 yards, while Sam Ehlinger led the team with 88 passing yards and two touchdowns on 10/11 completions. That should bolster Ehlinger’s confidence as he looks to get more exposure going forward in the preseason. Michael Pittman Jr. helped the passing attack with 30 receiving yards on just two catches and three targets, but it’s not clear how Indianapolis will handle his load the rest of the way in the preseason. What’s clearer is that the Colts’ defense can make noise after netting three interceptions against the Bills.

The Colts are 5-4-1 against the spread in their last 10 games in the preseason. The Under is 7-3 in the Colts’ last 10 preseason home games.

Writer’s Prediction

The Lions win, 26-23.

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