Los Angeles Rams vs Arizona Cardinals Predictions, Picks, Odds, and Betting Preview | NFL Week 3 – September 25, 2022

The Los Angeles Rams and the Arizona Cardinals face off in an interesting battle between 1-1 teams this Sunday. Check out our preview of this Rams vs Cardinals game in Week 3 of the 2022 NFL regular season.

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Betting Preview for the Los Angeles Rams vs Arizona Cardinals Week 3 Game on September 25, 2022

Where: McFadden’s Restaurant and Saloon, Glendale, AZ

When: Sunday, September 25, 2022, 4:25 PM ET

Line: Los Angeles Rams (-4.5) vs Arizona Cardinals (+4.5) – view all 2022 NFL lines

TV Broadcast: NFL Network

Betting on the Los Angeles Rams (-4.5)

Regular Season Record: 1-1

The Rams prevented a 0-2 start to their season with a 31-27 home win over the Atlanta Falcons last Sunday. Matthew Stafford went 27/36 for 272 passing yards (3 touchdowns, 2 INT) while Darrell Henderson rushed 10 times for 47 yards and a touchdown. There is still some more work to be done for the Rams to smoothen their performance going forward, but it’s nice for them to finally get the monkey off their back with a victory. Cooper Kupp also had another mesmerizing showing in Week 2 with 108 receiving yards and two touchdowns on 11 catches. He’ll be a handful for Arizona’s defense.

The Rams are 3-2 against the spread in their last five games overall.

Betting on the Arizona Cardinals (+4.5)

Regular Season Record: 1-1

The Cardinals shocked the NFL with a 29-23 road win over the Las Vegas Raiders in overtime in Week 2. Arizona was down by 20 points at the half but Kyler Murray led the Cardinals to a massive comeback, as they scored four touchdowns in the second half and overtime to just one by Las Vegas. It was a reminder that the Cardinals have the potential to explode on any given moment on the offensive end of the field, especially with Murray as quarterback. The Rams haven’t been solid on defense this season so far, and with Stafford seemingly so prone to turnovers, the Cardinals should get a fair shot at taking down Los Angeles in Week 3.

The Over is 4-1 in the Cardinals’ last five games as the home team.

Writer’s Prediction

The Cardinals win, 24-23.

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