Carolina Panthers vs Arizona Cardinals Predictions, Picks, Odds, and Betting Preview | NFL Week 10 – November 14, 2021

The Carolina Panthers take on the Arizona Cardinals in a Week 10 game down in Glendale. Will the Panthers score an upset in the desert? Or will the Cardinals add more to their list of victims this season? Check out our preview of this game below.

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Betting Preview for the Carolina Panthers vs Arizona Cardinals Regular Season Week 10 Game on November 14, 2021

Where: State Farm Stadium, Glendale

When: Sunday, November 14, 2021, 4:05 PM ET

Line: Carolina Panthers (+10) vs Arizona Cardinals (-10) – view all 2021 NFL lines

TV Broadcast: FOX

Betting on the Carolina Panthers (+10)

Regular Season Record: 4-5

The Panthers now have no choice but to start PJ Walker, with Sam Darnold expected to be out several weeks due to a fractured scapula. Walker is not going to play the Messiah for this Carolina team that had suffered a 24-6 home loss to the New England Patriots in Week 9. With uncertainty in the quarterback position, the Panthers should be better off letting Christian McCaffrey lead the offense. The running back returned to action in Week 9 after weeks of absence and rushed for 52 yards on 14 carries. He also led the team with 54 receiving yards on four catches. While it’s hard to trust Carolina to win games, keep in mind that the Panthers are 7-1 against the spread in their last eight games as the road underdog.

The Panthers are also 9-2 against the spread in their last 11 games away from home.

Betting on the Arizona Cardinals (-10)

Regular Season Record: 8-1

No Kyler Murray and DeAndre Hopkins? No problem for the Cardinals, who scored a decisive 31-17 win on the road against the San Francisco 49ers in Week 9 despite playing without their QB1 and WR1. Murray has a chance to return this week along with Hopkins, but having beaten the Niners on the road without those two says a lot about the quality of Arizona’s depth. Colt McCoy will get another start if Murray gets ruled out again, while Christian Kirk, Zach Ertz, and James Conner will be his top targets. Speaking of Conner, he could get plenty of touches against Carolina, with Chase Edmonds also suffering an ankle injury in Week 9. Conner exploded for 96 rushing yards and two touchdowns on 21 carries against San Francisco.

The Cardinal are 6-1 against the spread in their last seven games overall.

Writer’s Prediction

The Cardinals win, 27-16.

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