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Pittsburgh Steelers vs San Francisco 49ers Predictions, Picks, Odds, and Betting Preview – NFL Week 3 – September 22 2019

Pittsburgh Steelers vs San Francisco 49ers Predictions, Picks, Odds, and Betting Preview – NFL Week 3 – September 22 2019

The San Francisco 49ers will make their home debut for the 2019 NFL season, and they’ll come over to Santa Clara with a wave of confidence with the way they’re starting the season. The Pittsburgh Steelers, on the other hand, need to sort things fast before it’s too late. And they have to do it without the ailing Ben Roethlisberger. The Steelers are +1000 to win the AFC North, while the 49ers are +300 to win the NFC West.

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Betting Preview for the Pittsburgh Steelers vs San Francisco 49ers NFL Regular Season Week 3 Game on September 22, 2019

Where: Levi’s Stadium, Santa Clara

When: Sunday, September 22, 2019, 4:25 PM ET

Line: Pittsburgh Steelers (odds) vs. San Francisco 49ers (odds) – view all 2019 NFL lines

TV Broadcast: CBS

Betting on the Pittsburgh Steelers (0-2)

The Steelers did not escape the football gods’ wrath on starting quarterbacks in Week 2, as they just lost Ben Roethlisberger for the rest of the season after he sustained a shoulder during the team’s 28-26 home loss to the Seattle Seahawks last Sunday. Big Ben’s situation leaves the Steelers giving Mason Rudolph the access to the starting quarterback gig. Rudolph took the field against the Seahawks after Roethlisberger’s exit and passed for 112 yards and touchdowns with an interception on 12 of 19 completions. The Steelers are also uncertain if running back James Conner will play in Week 3. Conner hurt his knee in the Seattle game, but said in reports that he’s confident about his availability against the 49ers. The Steelers’ backup plan for a possible Conner absence is Jaylen Samuels, who has shown flashes of effectiveness when given enough time to play. The Steelers also get a boost to their defense after trading with the tanking Miami Dolphins for Minka Fitzpatrick, who’ll play safety for Pittsburgh.

The under is 6-1 in the Steelers’ last seven road games.

Betting on the San Francisco 49ers (2-0)

The last time before this year that the Niners started a season with back-to-back wins was way back when Colin Kaepernick was still starting for them in 2012. In their last game, the 49ers thumped the Cincinnati Bengals on the road, 41-17, thanks in large part to their backfield that went crazy on the ground. Matt Breida had 121 of the team’s 259 rushing yards, while Raheem Mostert had 83. Jeff Wilson rushed for only 34 yards on 10 carries, but had two scores. San Francisco could end up replicating those numbers with or without Tevin Coleman against the Steelers’ defense that got burned for 151 rushing yards and a touchdown by the Seahawks.  Coleman did not play in Week 2 after suffering a high-ankle sprain in Week 1 against the Tampa Bay Buccaneers. But don’t discount the threat of San Francisco’s passing attack. Jimmy Garropolo is coming off a three-touchdown game and he’ll be staring at the Steelers’ stop unit that surrendered passing yards in Week 3.

The Niners are 3-2 against the spread (ATS) in their last five home games.

Writer’s Prediction

The Steelers win, 26-23.

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Written by Ryan

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