Browns vs Chargers Predictions, Picks, Odds

The Cleveland Browns and the Los Angeles Chargers are both 3-1 after four weeks of football. Which between them will snag their fourth win in Week 5? Check out our preview of this game between legitimate AFC title contenders below.

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Betting Preview for the Cleveland Browns vs Los Angeles Chargers Regular Season Week 5 Game on October 10, 2021

Where: SoFi Stadium, Inglewood

When: Sunday, October 10, 2021, 4:05 PM ET

Line: Cleveland Browns (+2.5) vs Los Angeles Chargers (-2.5) – view all 2021 NFL lines

TV Broadcast: CBS

Betting on the Cleveland Browns (+2.5)

Regular Season Record: 3-1

The Browns picked up their third win of the season by taking down the Minnesota Vikings on the road last Sunday, 14-7. It was another impressive performance for the Browns’ defense, which is now fourth in the league with just 16.8 points allowed per game and second with only 250.2 total yards surrendered per contest. The Browns’ defense seems legit and has the tools to slow down the Chargers. Myles Garrett is a man on a mission, whose thirst for quarterbacks appears unquenchable. Garrett leads the NFL with six sacks while Jadeveon Clowney has two. Those two will be trouble even for LA’s offensive line that has been decent this season, thus far. The Chargers can’t say their pass protection is elite until they pass the Browns test. On offense, Baker Mayfield will look to recover from a subpar performance against the Vikings in which he went 15/33 for 155 passing yards and zero touchdowns. In any case, the Browns still have the pair of Nick Chubb and Kareem Hunt that can burrow holes on LA’s stop unit.

The Browns are 4-0 against the spread in their last four games as a road underdog.

Betting on the Los Angeles Chargers (-2.5)

Regular Season Record: 3-1

It’s not just Cleveland that will be parading a stout defense in this game. The Chargers are also doing fine on that side of the field, as they are seventh in the league with 18.5 points allowed per game and ninth with 332.0 total yards surrendered per contest. Those numbers are actually more impressive than what they appear to be on paper when you consider the fact that their last two wins were against the Kansas City Chiefs and the Las Vegas Raiders, two teams with high-powered offenses. The Chargers are also complementing their defense with a solid attack that is being powered by Justin Herbert. The former Oregon Ducks star continues to make the Miami Dolphins wince for taking Tua Tagovailoa over him. Herbert passed for 222 yards and three touchdowns with zero interceptions on 25/38 completions in their 28-14 win over the Raiders in Week 4. With the Browns struggling on offense, the Chargers’ defense should have LA get control of the ball most of the time in this upcoming match.

The Chargers are 5-0 against the spread in their last five vs. AFC teams.